D. Dixon, S. Ley, A. Polara
Oct 19, 2001
Citations
0
Influential Citations
36
Citations
Journal
Organic letters
Abstract
[reaction--see text] The butane-2,3-diacetal (BDA) desymmetrized glycolic acid building block 1 undergoes efficient and highly diastereoselective lithium enolate aldol reactions with both aromatic and aliphatic aldehydes to afford, after an acidic methanolysis deprotection step, the enantiopure anti-2,3-dihydroxy esters in good yield.