J. Chong, L. Hegedus
Jan 29, 2004
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0
Influential Citations
10
Citations
Journal
Organometallics
Abstract
Treatment of N-Boc-1-ferrocenylethylamine or N-Boc-ferrocenylmethylamine with 2 equiv of n-BuLi results in selective N,1‘-dimetalation. Trapping of the dianions with various electrophiles is a convenient route to unsymmetrical 1,1‘-disubstituted ferrocenes. Under similar conditions, the pivalamide of 1-ferrocenylethylamine undergoes predominantly N,2-dilithiation while urea derivatives give mixtures of regioisomers.