D. Rina, M. Nirmal, C. Vivek
Apr 24, 2018
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Abstract
Diethyl ethoxy-methylenemalonate the versatile reagent used to synthesize pyrazolopyrimidopyrimidines (3) as antimicrobial agents from the reaction between EMME and 1substituted 3-(methylthio) 3H-pyrazolo [3,4-d]pyrimidine-4-amines (1) using Gould Jacob reaction. A comparison of conventional and microwave supported solvent-free reaction has been studied.