Ren-Shen Lee, Jen-Ming Yang, Kai Huang
Jul 1, 1999
Citations
0
Influential Citations
19
Citations
Journal
Polymer Journal
Abstract
The preparation and characterization of polymers derived from hydroxyproline were investigated. Two new polymers of poly(trans-4-hydroxy-N-benzyloxycarbonyl-L-proline) [poly(N-Z-Hpr-OH)] and poly(trans-4-hydroxy-N-benzyloxycarbonyl-L-proline ester) [poly(N-Z-Hpr-OMe)], with easily removable pendant N-benzyloxycarbonyl group, were prepared. Weight-average molecular weight (Mw) of about 254000 and 33000 were obtained via esterification or transesterification, using stannous octoate as a catalyst, at 140°C under vacuum (20 mmHg) for 16 h. Removal of the N-benzyloxycarbonyl group by catalytic transfer hydrogenation yielded pseudopoly(trans-4-hydroxy-L-proline ester) [poly(Hpr-OMe·HCl)].