H. Yorimitsu, K. Wakabayashi, H. Shinokubo
Jan 15, 1999
Citations
0
Influential Citations
30
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Heating a mixture of 2-iodoacetamide and 5-hexen-1-ol in water at 75 °C in the presence of a water-soluble radical initiator, 4,4′-azobis(4-cyanopentanoic acid), provided γ-(4-hydroxybutyl)-γ-lactone in 95% yield. The use of 2-iodoacetic acid in place of 2-iodoacetamide also gave the same γ-lactone in 93 % yield.