P. Shanmugasundaram, N. Harikrishnan, M. V. Aanandini
Jul 7, 2011
Citations
0
Influential Citations
7
Citations
Journal
ChemInform
Abstract
Ethyl-5-amino-8-(4-halophenyl)-2-methyl-4,7-dioxo-3,4,5,6,7,8-hexahydro pyrido(2,3-d) pyrimidine-6-carboxylate and ethyl-5-amino-8-(4-halophenyl)-2-amino-4,7 dioxo-3,4,5,6,7,8 hexahydropyrido(2,3-d)pyrimidine-6-carboxylate derivatives have been synthesized through nucleophilic substitution reactions with the use of amidines, followed by 4haloanilines and malonic acid. These synthesized novel derivatives have been confirmed by elemental analysis, IR, 1 H NMR and mass spectra. These novel derivatives have also been screened for antibacterial, antifungal and antitumor activity.