V. Moreira, T. Vasaitis, V. Njar
Dec 1, 2007
Citations
0
Influential Citations
44
Citations
Journal
Steroids
Abstract
A series of novel 1H- and 2H-indazole derivatives of the commercially available dehydroepiandrosterone acetate have been synthesized and tested for inhibition of human cytochrome 17alpha-hydroxylase-C(17,20)-lyase (CYP17), androgen receptor (AR) binding affinity, and cytotoxic potential against three prostate cancer (PC) cell lines.