A. Yahyazadeh, Z. Ghasemi
Apr 15, 2013
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0
Influential Citations
13
Citations
Journal
European Chemical Bulletin
Abstract
A series of thiourea derivatives have been synthesized. Thiourea derivatives show a broad spectrum of biological activities such as antibacterial, antiviral, anticancer, anticonvulsion, analgesic an HDL-elevating. Ethyl isothiocyanate and aromatic amines were mixed and stirred at room temperature in acetone for 15h to give the corresponding thioureas in high yields. Their structures were confirmed by IR and 1 H-NMR. By addition e-donor groups to aromatic amines, thioureas were synthesized in high yields.