Bolun Hu, Chun-Lin Li, Zhiyong Liao
Nov 8, 2013
Citations
0
Influential Citations
4
Citations
Journal
Synlett
Abstract
Abstract A tetrabutylammonium bromide catalyzed trifluoromethylation/cyclization reaction of o-aralkynylaryl aldehydes with trimethyl(trifluoromethyl)silane and cesium fluoride has been developed. A variety of 1-alkylidene-3-(trifluoromethyl)phthalans were prepared in moderate to excellent yields by tandem nucleophilic addition and cyclization.