Kimie Imuro, T. Hanafusa
May 1, 1976
Citations
0
Influential Citations
16
Citations
Journal
Bulletin of the Chemical Society of Japan
Abstract
Spontaneous trifluoroacetylation at the β position of the pyrrole ring in 1-(2-aminophenyl)-2,5-dimethylpyrrole (1) was observed in trifluoroacetic acid. The half-life of the reaction was about 3.5 h at 25 °C. This unexpected result might be explained in terms of the 1,5-participation of the amino group in the electrophilic substitution reaction.