10 papers analyzed
Some studies suggest finasteride may cause erectile dysfunction, particularly in men with benign prostatic hyperplasia or younger men, while other studies indicate it does not impair erectile function or that its effects can be mitigated with coadministered treatments.
13 papers analyzed
Finasteride is a medication commonly used to treat benign prostatic hyperplasia (BPH) and male pattern hair loss (MPHL). There has been ongoing debate and research regarding its potential side effects, particularly its impact on erectile dysfunction (ED). This synthesis aims to present a cohesive analysis of the research findings related to the question: Does finasteride cause erectile dysfunction?
Association with ED in BPH Patients:
Impact on MPHL Patients:
Persistent Sexual Side Effects:
Animal Studies:
Combination Therapy:
Comparative Studies:
Neuroactive Steroid Levels:
The research indicates that finasteride is associated with an increased risk of erectile dysfunction in men treated for benign prostatic hyperplasia, but the evidence is less clear for those treated for male pattern hair loss. Persistent sexual side effects, including erectile dysfunction, have been reported in some men even after discontinuation of the drug. Combination therapy with tadalafil may help mitigate these effects. Other risk factors for erectile dysfunction, such as age and comorbid conditions, also play a significant role. Further well-designed studies are needed to fully understand the mechanisms and long-term effects of finasteride on erectile function.
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