Hypothyroidism sweating
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Hypothyroidism and Sweating: An Overview
Introduction to Hypothyroidism and Sweating
Hypothyroidism, a condition characterized by an underactive thyroid gland, affects various bodily functions, including sweating. The thyroid gland plays a crucial role in regulating metabolism, and its dysfunction can lead to noticeable changes in sweat production and composition.
Reduced Sweating in Hypothyroidism
Diminished Sweating and Skin Changes
One of the hallmark symptoms of hypothyroidism is reduced sweating. Patients with hypothyroidism often experience dry, coarse skin due to decreased sweat production. This reduction in sweating can lead to painful cracks and fissures in the palms and soles, as well as a tendency towards hyperkeratosis, where the skin becomes thickened and rough .
Cytologic Changes in Eccrine Sweat Glands
Biopsy studies have shown specific cytologic changes in the eccrine sweat glands of patients with hypothyroidism. These changes are particularly evident in patients who have been under treatment for less than four months, but can also be seen in some patients treated for a year or longer. These findings suggest that skin biopsies could be a useful diagnostic tool for hypothyroidism when conventional tests are impractical .
Abnormal Sweat Electrolyte Concentrations
Sodium and Chloride Levels in Sweat
Research indicates that thyroid dysfunction can lead to abnormal concentrations of electrolytes in sweat. In hypothyroidism, the concentration of sodium in sweat is typically increased, a condition known as myxedema . Additionally, elevated sweat chloride concentrations have been observed in hypothyroid patients, which can sometimes lead to misdiagnosis of conditions like cystic fibrosis .
Sweat Tests in Congenital Hypothyroidism
A study investigating sweat sodium concentrations in infants with congenital primary hypothyroidism found that sweat sodium levels were within normal ranges for all patients. This suggests that while electrolyte abnormalities can occur, they may not be present in all cases of hypothyroidism .
Conclusion
Hypothyroidism significantly impacts sweat production and composition, leading to reduced sweating and changes in sweat electrolyte concentrations. These alterations can contribute to various skin issues and may serve as diagnostic indicators. Understanding these changes is crucial for the effective management and diagnosis of hypothyroidism.
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