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These studies suggest that hypertension is a major risk factor and contributor to cardiovascular diseases, but not a cardiovascular disease itself.
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Hypertension and Cardiovascular Disease Risk
Hypertension is widely recognized as a significant risk factor for various cardiovascular diseases (CVDs). It is strongly associated with conditions such as coronary artery disease, left ventricular hypertrophy, valvular heart diseases, cardiac arrhythmias, cerebral stroke, and renal failure . The relationship between blood pressure and cardiovascular events is continuous, meaning that even high-normal blood pressure can increase the risk of cardiovascular and renal events.
Hypertension and Diabetes
In individuals with diabetes, hypertension is particularly prevalent and contributes significantly to the high incidence of cardiovascular diseases. Up to 75% of cardiovascular diseases in diabetic patients may be attributable to hypertension, underscoring the need for aggressive blood pressure management in this population .
Mechanisms of Hypertension-Induced Cardiovascular Damage
Hypertension exerts its deleterious effects on the cardiovascular system primarily through mechanical stress on the heart and blood vessels. This stress leads to hypertensive heart disease, congestive heart failure, and hypertensive vascular disease, which affects both large and small arteries. Additionally, hypertension accelerates the process of atherosclerosis, increasing the risk of myocardial infarction and stroke .
Hypertension and Cardiac Arrhythmias
Hypertension is also a common cause of various cardiac arrhythmias, particularly atrial fibrillation. Effective blood pressure control can help prevent the development of these arrhythmias, highlighting the close relationship between hypertension and cardiac rhythm disorders.
Epidemiology of Hypertension
Hypertension is the leading cause of cardiovascular disease and premature death worldwide. Despite the widespread use of antihypertensive medications, the prevalence of hypertension has increased, especially in low- and middle-income countries. In 2010, approximately 31.1% of adults globally had hypertension, with higher prevalence rates in low- and middle-income countries compared to high-income countries.
Economic Burden of Hypertension
The economic impact of hypertension is substantial. In the United States alone, hypertension was a primary or contributing cause of over 427,000 deaths in 2014, with associated healthcare costs amounting to $51.2 billion per year. Reducing the health and economic burden of hypertension is a public health priority.
While hypertension itself is not classified as a cardiovascular disease, it is a major risk factor and a significant contributor to the development and progression of various cardiovascular conditions. Effective management of hypertension is crucial in preventing cardiovascular diseases and reducing the associated health and economic burdens.
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