Tongkat ali
Pro Research Analysisby 
Searched over 200M research papers for "tongkat ali"
Consensus Meter
The Benefits and Effects of Tongkat Ali (Eurycoma longifolia)
Introduction to Tongkat Ali
Tongkat Ali, scientifically known as Eurycoma longifolia, is a traditional medicinal plant native to Southeast Asia. It is commonly referred to as "Malaysian ginseng" and has been used for centuries for its purported health benefits, including enhancing libido, improving energy levels, and treating various ailments .
Erectile Function Improvement
Clinical Efficacy on Erectile Dysfunction
Research has investigated the efficacy of Tongkat Ali in improving erectile function. A systematic review and meta-analysis of randomized controlled trials found that while there was no significant difference in the mean improvement of erectile function between Tongkat Ali and placebo groups overall, there was a notable improvement in subjects with lower baseline erectile function scores. This suggests that Tongkat Ali may be more effective in individuals with more severe erectile dysfunction.
Stress and Mood Enhancement
Impact on Stress Hormones and Psychological Mood
Tongkat Ali has also been studied for its effects on stress and mood. A study involving 63 moderately stressed subjects found that supplementation with Tongkat Ali significantly reduced levels of tension, anger, and confusion. Additionally, it improved the stress hormone profile by reducing cortisol levels and increasing testosterone levels. These findings indicate that Tongkat Ali may help mitigate the effects of chronic stress and improve overall mood.
Traditional and Pharmacological Uses
Ethnobotanical Applications
Traditionally, Tongkat Ali has been used for a variety of purposes, including as an antimalarial, aphrodisiac, anti-diabetic, antimicrobial, and anti-pyretic agent . The plant is rich in bioactive compounds such as quassinoids and alkaloids, which contribute to its diverse pharmacological activities.
Antimicrobial and Antiparasitic Properties
Several studies have highlighted the antimicrobial and antiparasitic potential of Tongkat Ali. Extracts from the plant have shown efficacy against various bacteria and fungi, supporting its traditional use as an antiseptic and treatment for infections . This antimicrobial activity could be beneficial for developing new natural therapies and pharmaceutical treatments.
Safety and Toxicology
Toxicity and Safety Evaluation
The safety profile of Tongkat Ali has been extensively studied. Acute and subchronic toxicity studies have shown that the plant's extracts are generally safe, with no significant adverse effects observed at normal dosages. The lethal dose (LD50) for the aqueous extract is more than 3000 mg/kg, indicating a high safety margin . These findings support the safe use of Tongkat Ali in dietary supplements and traditional medicine.
Conclusion
Tongkat Ali (Eurycoma longifolia) is a versatile medicinal plant with a wide range of health benefits. It has shown potential in improving erectile function, reducing stress, and enhancing mood. Additionally, its traditional uses and antimicrobial properties make it a valuable natural remedy. While current evidence supports its efficacy and safety, further research is warranted to fully understand its therapeutic potential and optimize its use in modern medicine.
Sources and full results
Most relevant research papers on this topic
Efficacy of Tongkat Ali (Eurycoma longifolia) on erectile function improvement: systematic review and meta-analysis of randomized controlled trials.
Effect of Tongkat Ali on stress hormones and psychological mood state in moderately stressed subjects
An Evidence-Based Systematic Review of Tongkat Ali (Eurycoma longifolia) by the Natural Standard Research Collaboration
Tongkat Ali (Eurycoma longifolia Jack): a review on its ethnobotany and pharmacological importance.
Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology
Simultaneous quantitation of six major quassinoids in Tongkat Ali dietary supplements by liquid chromatography with tandem mass spectrometry.
Phytochemical screening and antimicrobial activity of root and stem extracts of wild Eurycoma longifolia Jack (Tongkat Ali)
Tongkat Ali as a Potential Herbal Supplement for Physically Active Male and Female Seniors—A Pilot Study
A Systematic Review on Antimicrobial and Antiparasitic Activity of Eurycoma longifolia Jack (Tongkat Ali)
Evaluation of Acute 13-Week Subchronic Toxicity and Genotoxicity of the Powdered Root of Tongkat Ali (Eurycoma longifolia Jack)
Try another search
What are the facial recognition algorithms available
The potential of digital twin technology in optimizing industrial processes, manufacturing, and product design.
user experience
The role of artificial photosynthesis in renewable energy generation.
What are the implications of deep-sea exploration for human health?
The safety and ethical implications of CRISPR and gene editing in humans.