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10 papers analyzed
These studies suggest that the best treatments for influenza include vaccination, antiviral therapy (such as neuraminidase inhibitors and newer drugs like baloxavir marboxyl), and combination antiviral treatments, while corticosteroids may increase risks and require caution.
20 papers analyzed
Influenza, commonly known as the flu, is a significant cause of morbidity and mortality worldwide. Effective management of influenza includes both preventive measures, such as vaccination, and therapeutic interventions, including antiviral medications. This synthesis aims to present the best treatments for influenza based on recent research findings.
Vaccination as Prevention:
Neuraminidase Inhibitors (NAIs):
Adamantanes:
Combination Antiviral Therapy:
Novel Antiviral Agents:
Adjunctive Therapies:
Prophylactic Use of Antivirals:
The best treatments for influenza involve a combination of preventive and therapeutic strategies. Vaccination remains the cornerstone of prevention, with both inactivated and live, attenuated vaccines playing crucial roles. Neuraminidase inhibitors are the primary antiviral treatment, effective in reducing symptoms and complications when administered early. Combination antiviral therapies and novel agents like favipiravir and baloxavir marboxyl show promise for future treatment options. Adjunctive therapies targeting the host inflammatory response may also enhance treatment outcomes. However, the use of corticosteroids should be approached with caution due to potential adverse effects. Continued research and clinical trials are essential to optimize influenza management and address emerging resistance.
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