A. Kaiser, Miriam Balbi
Mar 12, 1999
Citations
0
Influential Citations
15
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract Reaction of lithiated 4-methoxybenzylisocyanide with homochiral amino acid derived N -tosyl- and N -diphenylphosphinoylaziridines proceeds diastereoselectively to provide N -protected 3-isocyanoamines. Separation of the diastereomers of these adducts or the corresponding formamides, and subsequent transformations, lead to 1,3-diamines and their monoprotected and differentially bisprotected derivatives.