A. W. Douglas, M. Fisher, J. J. Fishinger
Jul 1, 1977
Citations
0
Influential Citations
15
Citations
Journal
Journal of medicinal chemistry
Abstract
4-Chlorobenzaldehyde 1-(4-chlorophenyl)-4(1H)-pyridinylidene hydrazone fluorusulfonate (4) was found to have excellent anticoccidial activity in chickens. The synthesis and biological evaluation of related analogues are presented. Presumably 4 shares a common mechanism of action with robenidine (25) since it was not active on a robenidine tolerant strain of E. tenella. Structural comparisons of the two molecules are presented.