Akira Miyashita, H. Takaya, T. Souchi
1984
Citations
0
Influential Citations
184
Citations
Quality indicators
Journal
Tetrahedron
Abstract
Abstract Racemic 2, 2'-bis(diphenylphosphino)-l, 1'-binaphthyl has been synthesized from 2, 2'-dihydroxy-l, l'-binaphthyl in two steps and resolved into optically pure ( R )-(+) and ( S ) (-) enantiomers by the use of (+)-di-μ-chlorobis[( S )-N,N-dimethyl-α-phenylethylamine-2C,N]dipalladium. This new axially dissymmetric bis(triaryl)phosphine serves as an excellent ligand for Rh(l)-catalyzed asymmetric hydrogenations of α-(acylamino) acrylic acids or esters. Factors controlling the enantioselectivity and mechanistic aspects are discussed on the basis of the 31 P-NMR measurements