Paper
2-Deoxy-2-fluoro-D-glycosyl fluorides. A new class of specific mechanism-based glycosidase inhibitors.
Published Jun 15, 1988 · S. G. Withers, K. Rupitz, Ian P. Street
The Journal of biological chemistry
Q1 SJR score
119
Citations
2
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
In Vitro Study
Highly CitedStudy Snapshot
2-deoxy-2-fluoro-D-glycosyl fluorides effectively trap covalent glycosyl enzyme intermediates, providing a new approach for mechanism-based glycosidase inhibitors.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
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Citations
Towards the synthesis of a 2-deoxy-2-fluoro-d-mannose building block and characterisation of an unusual 2-S-phenyl anomeric pyridinium triflate salt via 1 → 2 S-migration.
This study successfully synthesized a 2-deoxy-2-fluoro-d-mannose building block and identified an unexpected anomeric pyridinium salt, which can be used for further anomeric manipulation.
2024·1citation·Sean T. Evans et al.·Carbohydrate research
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Distributable, Metabolic PET Reporting of Tuberculosis
[18F]FDT, a bacterium-specific PET tracer, can be produced globally from readily available [18F]FDG, potentially democratizing access to TB-specific diagnostics.
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bioRxiv
Development of a 1,2-difluorofucoside activity-based probe for profiling GH29 fucosidases.
The 1,2-difluorofucoside activity-based probe effectively identifies and studies a wide variety of GH29 fucosidases, including those in gut microbiota, with broader utility.
2021·8citations·Yvette M C A Luijkx et al.·Organic & biomolecular chemistry
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Synthetic Fluorinated L-Fucose Analogs Inhibit Proliferation of Cancer Cells and Primary Endothelial Cells.
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