J. Glister, K. Vaughan, K. Biradha
Jul 15, 2005
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0
Influential Citations
11
Citations
Journal
Journal of Molecular Structure
Abstract
Abstract (2S,7R,11S,16R)-1,8,10,17-tetraazapentacyclo[8.8.1.18,17.02,7.011,16]icosane (7) has been synthesized by reaction of commercial 1,2-cyclohexanediamine with formaldehyde in dimethylformamide solution. The crystal structure of 7 has been determined by single crystal X-ray diffraction analysis. The crystal structure of 7 shows that the geometry of the N-atoms is the less likely cis-configuration, the precise configuration that was claimed by previous investigators to be unlikely to exist! The C–C–C bond angles within the cyclohexane rings of 7 are in the range 113.9(7)–124.6(8)°, indicating that the cyclohexane rings are more planar than chair-like. The N–C–N bond angles around the bridging methylene groups are similarly distorted from tetrahedral geometry. The crystal structure of 7 is compared with the previously reported structures of 1,3,6,8-tetraazatricyclo[4.4.1.13,8]dodecane(1) and 1,4-dimethano-dibenzo[d,i]-1,3,6,8-tetrazecine(2). The title compound (7) {C16H28N4}, crystallizes in the orthorhombic, space group Fdd2, with lattice constants: a=11.9733(17) A, b=12.8485(18) A, c=19.095(3) A, α=90°, β=90°, γ=90°, V=2937.5(7) A3, Z=8, Dc=1.250 mg m−3, F(000)=1216, R1=0.0834, wR2=0.2255.