Paper
The 5-HT1A Receptor: Signaling, Desensitization, and Gene Transcription
Published 1996 · P. Albert, P. Lembo, J. Storring
Neuropsychopharmacology
Q1 SJR score
136
Citations
6
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Antianxiety and antidepressant agents enhance serotonergic neurotransmission through desensitization of 5-HT1A autoreceptors, and understanding this receptor's regulation is crucial for their therapeutic actions.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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Citations
The serotonin 1A receptor promoter polymorphism, rs6295, is associated with morphofunctional features
The serotonin 1A receptor promoter polymorphism, rs6295, is associated with morphofunctional features and body weight gain, potentially aiding in obesity prevention and treatment strategies.
2024·0citations·A.A. Vasileva·Moscow University Anthropology Bulletin (Vestnik Moskovskogo Universiteta Seria XXIII Antropologia)
Moscow University Anthropology Bulletin (Vestnik Moskovskogo Universiteta Seria XXIII Antropologia)
5-Hydroxytryptophan Reduces Levodopa-Induced Dyskinesia via Regulating AKT/mTOR/S6K and CREB/ΔFosB Signals in a Mouse Model of Parkinson’s Disease
5-HTP effectively reduces L-DOPA-induced dyskinesia in Parkinson's disease mice by regulating hyperactivated striatal AKT/mTOR/S6K and CREB/FosB signaling.
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Deep brain stimulation (DBS) in preclinical models shows antidepressant-like effects through various neurochemical changes, including changes in serotonin levels and dopamine levels.
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European Neuropsychopharmacology
Systematic identification of candidate genes associated with aggressive behavior: A neurogenetic approach
Aggressive behavior is linked to neurotransmitter genes, which could serve as early biomarkers for diagnosing and developing drug targets for therapeutics.
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Effects of a Cc2d1a/Freud-1 Knockdown in the Hippocampus on Behavior, the Serotonin System, and BDNF
Cc2d1a/Freud-1 knockdown in the hippocampus impairs memory and reduces antidepressant effects, suggesting its involvement in depressive disorders through the 5-HT1A receptor and BDNF.
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International Journal of Molecular Sciences