J. Gallagher, Marie-Delphine H Le Bas, Claire M. Coleman
Mar 15, 2007
Citations
0
Influential Citations
0
Citations
Journal
Acta crystallographica. Section C, Crystal structure communications
Abstract
The title compound, C(18)H(13)FN(2)OS, is the first structural example of a [6-5] fused ring incorporating the 2,3-dihydro-4H-imidazo[5,1-b][1,3]thiazin-4-one molecular scaffold. The six-membered 2,3-dihydro-1,3-thiazin-4-one ring adopts an envelope conformation, with the S-CH(2) C atom displaced by 0.761 (2) A from the five-atom plane (all within 0.05 A of the mean plane). The imidazole ring is planar. The phenyl ring is twisted from coplanarity with the imidazole ring by 23.84 (5) degrees and the 4-fluorophenyl ring is twisted by 53.36 (6) degrees , due to a close C(aryl)-H...O=C contact with the thiazin-4-one carbonyl O atom. The primary intermolecular interaction involves a CH(2) group with the F atom [C...F = 3.256 (2) A and C-H...F = 137 degrees ].