T. Nguyen, P. Retailleau
Jul 7, 2017
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0
Influential Citations
43
Citations
Journal
Organic letters
Abstract
A catalyst-free, redox-neutral, and completely atom-economical synthesis of sultams by simply heating 2-nitrochalcones with elemental sulfur in 3-picoline or N-methylmorpholine is described. The S-N, C-S, and S═O bonds of the sulfonamide are efficiently formed between the nitrogen atom of the 2-nitro group and the α-carbon of the chalcones and elemental sulfur with the migration of two oxygen atoms from the 2-nitro group to the sulfur atom.