W. Denny
Aug 31, 2002
Citations
5
Influential Citations
276
Citations
Quality indicators
Journal
Current medicinal chemistry
Abstract
Acridine derivatives are one of the oldest classes of bioactives, widely used as antibacterial and antiprotozoal agents. Some work in these areas continues, but recent research has focused mainly on their use as anticancer drugs, because of the ability of the acridine chromophore to intercalate DNA and inhibit topoisomerase enzymes.