Carcinogenic Action of N-Methyl-N′-nitro-N-nitrosoguanidine

doi:10.1038/210962B0

Paper

DOI: 10.1038/210962B0

Carcinogenic Action of N-Methyl-N′-nitro-N-nitrosoguanidine

Published May 28, 1966 · T. Sugimura, M. Nagao, Yoshikiyo Okada

Nature

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100

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

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Study Snapshot

N-Methyl-N′-nitro-N-nitrosoguanidine (NG) is a potent carcinogenic agent, inducing mutations in bacteria and plants, and has been linked to various cancers.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Cell cycle was disturbed in the MNNG-induced initiation stage during in vitro two-stage transformation of Balb/3T3 cells.

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