Anti-oxidant, anti-fungal and anti-leishmanial activities of novel 3-[4-(1H-imidazol-1-yl) phenyl]prop-2-en-1-ones.

doi:10.1016/j.ejmech.2009.06.038

Paper

DOI: 10.1016/j.ejmech.2009.06.038

Anti-oxidant, anti-fungal and anti-leishmanial activities of novel 3-[4-(1H-imidazol-1-yl) phenyl]prop-2-en-1-ones.

Published Nov 1, 2009 · Tanvir Hussain, H. Siddiqui, M. Zia-ur-Rehman

European journal of medicinal chemistry

Q2 SJR score

Citations

Influential Citations

Full textSemantic Scholar

Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

Novel 3-[4-(1H-imidazol-1-yl) phenyl]prop-2-en-1-ones show promising anti-oxidant, anti-fungal, and anti-leishmanial activities.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Full text analysis coming soon...

References

DOI: 10.1016/j.ejmech.2008.08.010

Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives.

Compounds 15-17 and 24 show antibacterial activity, while compound 26 shows potential antifungal activity, making them potential lead compounds for developing novel antiviral agents.

2009·204citations·D. Sharma et al.·European journal of medicinal chemistry

European journal of medicinal chemistry

DOI: 10.1016/J.POLY.2007.11.015

Ferrocenyl chalcones containing anthracenyl group: Synthesis, X-ray crystal structures and electrochemical properties

Ferrocenyl chalcones with anthracenyl groups show high torsion angles and quenched fluorescence properties, potentially due to the ferrocenyl group.

2008·61citations·Younjung Jung et al.·Polyhedron

Polyhedron

DOI: 10.1016/j.bmcl.2007.12.023

Design, synthesis, and in vitro antitumor activity of new 1,4-diarylimidazole-2-ones and their 2-thione analogues.

New 1,4-diarylimidazole-2-one derivatives show potent antitumor activity against leukemic cell lines, with compound 13 showing particularly strong activity against MOLT-4 and SR cell lines.

2008·135citations·C. Congiu et al.·Bioorganic & medicinal chemistry letters

Bioorganic & medicinal chemistry letters

DOI: 10.1016/J.BMCL.2007.10.034

Synthesis and antioxidant properties of substituted 3-benzylidene-7-alkoxychroman-4-ones.

Substituted 3-benzylidene-7-alkoxychroman-4-one derivatives with catechol moiety exhibit excellent antioxidant activity, outperforming the reference drug Trolox in all tested methods.

2007·60citations·A. Foroumadi et al.·Bioorganic & medicinal chemistry letters

Bioorganic & medicinal chemistry letters

DOI: 10.1248/CPB.55.1014

Synthesis and antibacterial activity of bis[2-amino-4-phenyl-5-thiazolyl] disulfides.

Bis[2-amino-4-phenyl-5-thiazolyl] disulfides show promising antibacterial activity against Gram positive and negative bacteria, particularly Bacillus cereus and Pseudomonas aeruginosa.

2007·42citations·H. Siddiqui et al.·Chemical & pharmaceutical bulletin

Chemical & pharmaceutical bulletin

Citations

DOI: 10.1002/jhet.4385

Synthesis, anti‐microbial/radical scavenging and in‐silico investigations of a novel class of 4‐[(4 ʹ ‐hydroxymethylphenyl)‐ 1 H ‐1 ʹ ,2 ʹ ,3 ʹ ‐triazol‐1‐yl‐methyl]‐ 2 H ‐chromen‐2‐ones

A novel class of coumarinyl-triazoyl-phenyl methanol derivatives shows potential as potent antibacterial inhibitors, with in-vitro antibacterial, antifungal, and radical scavenging activities.

2021·2citations·Sowmiya Carmel Yesudass et al.·Journal of Heterocyclic Chemistry

Journal of Heterocyclic Chemistry

DOI: 10.3390/m1269

(E)-3-[4-(1H-Imidazol-1-yl)phenyl]-1-(4-methylphenyl)prop-2-en-1-one

The novel compound (E)-3-[4-(1H-imidazol-1-yl)phenyl]-1-(4-methylphenyl)prop-2-en-1-one) shows potential for antifungal activity against Aspergillus fumigatus, the causative agent for

2021·1citation·N. Bailey et al.·Molbank

Molbank

DOI: 10.1080/10406638.2021.1939069

Imidazole Appended Novel Phenoxyquinolines as New Inhibitors of α-Amylase and α-Glucosidase Evidenced with Molecular Docking Studies

Compound 7a, a novel imidazole appended phenoxyquinoline derivative, shows potent inhibitory activity against -amylase and -glucosidase, potentially reducing hyperglycemia.

2021·7citations·N. Lohitha et al.·Polycyclic Aromatic Compounds

Polycyclic Aromatic Compounds

DOI: 10.3390/M1184

(E)-3-(4-Chlorophenyl)-1-(2-fluoro-4-methoxyphenyl)-2-propen-1-one

The novel compound (E)-3-(4-chlorophenyl)-1-(2-fluoro-4-methoxyphenyl)-2-propen-1-one) shows potential as an antileishmanial agent due to its antiparasitic properties.

2021·5citations·N. Bailey et al.·Molbank

Molbank

DOI: 10.3390/molecules25215021

Deposition of Tetracoordinate Co(II) Complex with Chalcone Ligands on Graphene

This study successfully deposited a Co(II)-based complex with chalcone ligands on graphene, resulting in nanodroplets and microcrystallites at grain boundaries and defects.

2020·15citations·J. Hrubý et al.·Molecules

Molecules

DOI: 10.3390/cryst10050354

Halogen Bonding in New Dichloride-Cobalt(II) Complex with Iodo Substituted Chalcone Ligands

The new chalcone ligand 4I-L and its tetracoordinate Co(II) complex show promising properties, with iodine substituents playing a key role in non-covalent interactions and halogen bonding.

2020·7citations·Lukáš Masaryk et al.·Crystals

Crystals

DOI: 10.14233/ajchem.2020.22542

Synthesis and Biological Evaluation of Some Novel Quinoline based Chalcones as Potent Antimalarial, Anti-inflammatory, Antioxidant and Antidiabetic Agents

Novel quinoline-based chalcones show potent antimalarial, anti-inflammatory, antioxidant, and antidiabetic activities, potentially aiding in the design of new drugs.

2020·2citations·N. Peerzade et al.·Asian Journal of Chemistry

Asian Journal of Chemistry

DOI: 10.1016/J.POLY.2018.06.011

A combined experimental and computational study of a ruthenium(II) polypyridyl complex: Synthesis, characterization, electronic structures and spectral properties

The novel ruthenium(II) complex of [Ru(bpy) 2 (ipipH)](PF6 ) 2 shows electrostatic interaction as the dominant metal-ligand interaction.

2018·2citations·Yong Xia et al.·Polyhedron

Polyhedron

DOI: 10.1021/acsomega.8b00553

Synthesis and Preliminary Antimicrobial Analysis of Isatin–Ferrocene and Isatin–Ferrocenyl Chalcone Conjugates

Isatin-ferrocene and isatin-ferrocenyl chalcone conjugates show promising antimicrobial activity against human mucosal pathogen Trichomonas vaginalis, offering potential as new drug scaffolds against trichomonad infections.

2018·23citations·Amandeep Singh et al.·ACS Omega

ACS Omega