Neurological Activity of Lion’s Mane (Hericium erinaceus)

doi:10.14200/JRM.2017.6.0108

Paper

Neurological Activity of Lion’s Mane (Hericium erinaceus)

Published Dec 1, 2017 · Kevin Spelman, E. Sutherland, A. Bagade

UNKNOWN SJR score

25

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Abstract

Hericium erinaceus, most commonly known as lion’s mane, is an edible fungus, with a long history of use in Traditional Chinese Medicine. The mushroom is abundant in bioactive compounds including β-glucan polysaccharides; hericenones and erinacine terpenoids; isoindolinones; sterols; and myconutrients, which potentially have neuroprotective and neuroregenerative properties. Because of its anti-inflammatory properties and promotion of nerve growth factor gene expression and neurite (axon or dendrite) outgrowth, H. erinaceus mycelium shows great promise for the treatment of Alzheimer’s and Parkinson’s diseases. The fungus was well tolerated in two clinical studies, with few adverse events reported.

Study Snapshot

Key takeawayLion's mane mushroom shows potential in treating Alzheimer's and Parkinson's diseases due to its neuroprotective and neuroregenerative properties.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Neurological Activity of Lion’s Mane (Hericium erinaceus)

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