Azusa Kondoh, Masafumi Oishi, T. Takeda
Oct 20, 2015
Citations
0
Influential Citations
35
Citations
Journal
Angewandte Chemie
Abstract
A chiral bis(guanidino)iminophosphorane catalyzes enantioselective addition reactions of a 1,3-dithiane derivative as a pronucleophile. The chiral uncharged organosuperbase facilitates the addition of benzyloxycarbonyl-1,3-dithiane to aromatic N-Boc-protected imines to provide optically active α-amino-1,3-dithiane derivatives, which are valuable versatile building blocks in organic synthesis.