Paper
The antiviral agent 5-chloro-1,3-dihydroxyacridone interferes with assembly and maturation of herpes simplex virus.
Published Feb 1, 2002 · P. Akanitapichat, K. Bastow
Antiviral research
Q1 SJR score
32
Citations
0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
5-chloro-1,3-dihydroxyacridone inhibits herpes simplex virus assembly and maturation, resulting in reduced levels of capsids and encapsidated DNA.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
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Citations
A comprehensive spectral, photophysical and electrochemical study of synthetic water-soluble acridones. A new class of pH and polarity sensitive fluorescent probes
Water-soluble acridones show long lifetime values and potential as selective probes for different cellular environments and targets, depending on pH and solvent polarity.
2019·19citations·Ricardo C. Pereira et al.·Dyes and Pigments
Dyes and Pigments
Experimental Dissection of the Lytic Replication Cycles of Herpes Simplex Viruses in vitro
This study aims to dissect herpes simplex virus lytic replication cycles in vitro, aiding in the identification of anti-HSV compounds' mechanisms of action and improving antiviral efficacy.
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The Apical Region of the Herpes Simplex Virus Major Capsid Protein Promotes Capsid Maturation
The apical region of the herpes virus major capsid protein plays a crucial role in capsid maturation, promoting the formation of a stable angularized shell.
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Phytochemical screening, cytotoxicity and antiviral activity of hexane fraction of Phaleria macrocarpa fruits
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Synthesis and evaluation of the antitumor activity of polyhalo acridone derivatives
Polyhalo acridone derivatives show potent antitumor activity, with compounds 4d, 4o, 5j, and 5k showing good antineoplastic selectivity and survival rates above 50% in NIH3T3 mouse embryonic cells.
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