Tao Chen, Wen-bo Liu, Xiao Qian
Jan 1, 2021
Citations
2
Influential Citations
16
Citations
Journal
CNS Neuroscience & Therapeutics
Abstract
Perampanel is a highly selective and noncompetitive α‐amino‐3 ‐hydroxy‐5‐methyl‐4‐isoxazole propionate receptor (AMPAR) antagonist, which has been used as an orally administered antiepileptic drug in more than 55 countries. Recently, perampanel was shown to exert neuroprotective effects in hemorrhagic and ischemic stroke models via regulating blood–brain barrier (BBB) function.