Paper
Anti-inflammatory activity of 4-methoxyhonokiol is a function of the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB, JNK and p38 MAPK inactivation.
Published May 31, 2008 · H. Zhou, E. M. Shin, L. Guo
European journal of pharmacology
Q1 SJR score
120
Citations
1
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Non-RCT
Animal Study
Rigorous Journal
Highly CitedStudy Snapshot
4-methoxyhonokiol, a constituent from Magnolia obovata bark, exhibits anti-inflammatory properties by inhibiting iNOS and COX-2 expression in macrophages through down-regulation of JNK and p38 MAP kinase signal pathways and inhibition of
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
Inhibitory effect of obovatol on nitric oxide production and activation of NF-kappaB/MAP kinases in lipopolysaccharide-treated RAW 264.7cells.
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