Association of a MIND diet with the risk of dementia and brain structure in a French older population

doi:10.1002/alz.050386

Paper

Association of a MIND diet with the risk of dementia and brain structure in a French older population

Published Dec 1, 2021 · Aline Thomas, C. Féart, C. Helmer

Alzheimer's & Dementia

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Abstract

The MIND diet score for brain health is a 15‐item score combining neuroprotective dietary components (e.g. green leafy vegetables, nuts, berries, whole grains, fish). A higher MIND diet score was associated with slower cognitive decline and lower risk of Alzheimer’s disease; however, its relationship with brain structure has not yet been investigated. Taking advantage of a large population‐based cohort of older adults, we constructed a MIND diet score adapted to French dietary habits and we evaluated the associations of the score with the risk of dementia and Alzheimer’s disease (AD). In a secondary analysis, we investigated the cross‐sectional relationship between the MIND diet score and gray matter structure assessed by Magnetic Resonance Imaging (MRI).

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Study Snapshot

Key takeawayA higher MIND diet score in a French-adapted population is associated with slower cognitive decline and lower risk of Alzheimer's disease, as well as better gray matter structure.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Association of a MIND diet with the risk of dementia and brain structure in a French older population

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References

Citations

Adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet and exposure to selenium species: A cross-sectional study.

Adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet is associated with lower circulating concentrations of selenium and potentially neurotoxic selenoprotein P and selenate, potentially reducing cognitive decline.

Associations of Midlife Dietary Patterns with Incident Dementia and Brain Structure: Findings from the UK Biobank Study.

A healthy midlife diet, including a Mediterranean diet, is associated with reduced dementia risk and larger brain volumes in specific regions.

Joint association of daytime sleep behaviors and dietary quality with the risk of dementia: A large prospective cohort study

High daytime sleep behaviors and low dietary quality are significantly associated with higher risks of dementia, with high daytime sleep behaviors playing a decisive role.

Associations of Midlife Diet Quality with Incident Dementia and Brain Structure: Findings from the UK Biobank Study

Higher midlife diet quality, except for hPDI, is associated with a lower risk of dementia and larger brain volumes in specific regions.