Kari I. Kivirikko, Kari I. Kivirikko, Kazuo Suga
Dec 17, 1971
Citations
1
Influential Citations
22
Citations
Quality indicators
Journal
Biochemical and biophysical research communications
Abstract
Abstract Peptides of the structure (Pro-Pro-Gly) 5 and labeled with [ 14 C]proline in individual triplets were synthesized and used as substrates for the synthesis of hydroxyproline by protocollagen proline hydroxylase. The results indicated that the enzyme hydroxylated the peptide asymmetrically in that the fourth triplet from the NH 2 -terminal end was hydroxylated to a greater extent than any other triplet.