Bioactivity of genistein: A review of in vitro and in vivo studies.

doi:10.1016/j.biopha.2015.10.026

Paper

Bioactivity of genistein: A review of in vitro and in vivo studies.

Published Dec 1, 2015 · A. A. Ganai, Humaira Farooqi

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Q1 SJR score

210

Citations

7

Influential Citations

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Abstract

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Literature Review

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Study Snapshot

Genistein has potential health benefits, including anti-aging effects, cancer prevention, and cardioprotection, with its multidirectional action and low toxicity.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Bioactivity of genistein: A review of in vitro and in vivo studies.

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References

Citations

Genistein: A Promising Ally in Combating Neurodegenerative Disorders.

Genistein shows potential in reducing neurodegenerative disorders by improving cognitive performance, reducing hyperglycemia, and alleviating neuroinflammatory conditions.

Genistein and Aphid Probing Behavior: Case Studies on Polyphagous Aphid Species

Genistein is not a deterrent chemical against generalist aphid species, and is not recommended for practical application.

Infant mice fed soy-based formulas exhibit alterations in anxiety-like behaviours and the 5-HT system.

Early phytoestrogen exposure at levels comparable to soy-based infant formulas can alter anxiety-related behaviors and the serotonin system in mice.

Replacing Hydrolyzed Soybean Meal with Recombinant β-Glucosidase Enhances Resistance to Clostridium perfringens in Broilers Through Immune Modulation

Substituting conventional soybean meal with -glucosidase significantly reduced feed consumption and improved intestinal damage and immune dysfunctions caused by Clostridium perfringens infection in broilers.

Flavonoids in natural products for the therapy of liver diseases: progress and future opportunities

Flavonoids show potential in treating liver diseases through their hepatoprotective and molecular mechanisms, offering promising prospects for future clinical applications.

Identification of potential therapeutic targets for systemic lupus erythematosus based on GEO database analysis and Mendelian randomization analysis

ISG15 is a potential therapeutic target for systemic lupus erythematosus, and molecular docking technology reveals that genistein and flavopiridol show potential therapeutic effects by binding to ISG15.

Study on biotransformation and absorption of genistin based on fecal microbiota and Caco-2 cell

Fermentation of genistin by fecal bacteria produces small molecule metabolites that can be well absorbed systemically by the body.