Zhao Jin-mei
2008
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Journal
Hunan Agricultural Sciences
Abstract
Ethyl(R)-2-hydroxy-4-phenylbutanoate [(R)-HPBE] is an important intermediate for the synthesis of angiotensin-converting enzymeinhibitors(ACE) inhibitors such as enalapril and lisinopril etc.Mainly the synthesis routes and the research developments of(R)-HPBE by the method of biocatalyst at home and abroad were summarized in this article.