S. Cunha, B. R. D. Lima, A. R. Souza
2002
Citations
0
Influential Citations
37
Citations
Journal
Tetrahedron Letters
Abstract
The bismuth nitrate-mediated guanidylation of N-benzoylthioureas was studied. This salt proved to be an effective guanylating reagent and allowed the obtention of N-benzoyl-guanidines in good yields. The methodology described is a promising alternative to the use of toxic HgCl2 in the synthesis of polysubstituted guanidines.