Botulinum toxin treatment in patients with facial synkinesis.

doi:10.1007/978-3-642-85090-5_70

Paper

Botulinum toxin treatment in patients with facial synkinesis.

Published Dec 1, 1994 · R. Laskawi, W. Damenz, P. Roggenkämper

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

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22

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Abstract

Botulinum toxin therapy (BTT), originally applied to treat strabism (for review see [8]), is now established as a minimally invasive, successful therapy in a number of diseases. The treatment of mass movements (synkinesis) following paralysis of the facial nerve, which may have various etiologies, has recently been reported as another indication. First experiences with BTT, applied to several patients with such synkinesis, were published by Roggenkamper et al. [7]. This indication was also confirmed by case reports by other authors [2, 6]. According to Roggenkamper et al. [7] this treatment is effective for an average of 11 weeks after the first injection, according to patients’ personal assessment.

Study Snapshot

Key takeawayBotulinum toxin therapy (BTT) effectively treats facial synkinesis in patients with paralysis of the facial nerve, providing a minimally invasive treatment option for mass movements.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Botulinum toxin treatment in patients with facial synkinesis.

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References

Botulinum toxin injections in the treatment of seventh nerve misdirection.

Botulinum toxin injections can effectively correct eyelid deformity caused by seventh nerve misdirection without causing retracted eyelids when not smiling.

Electromyographic rehabilitation of facial function and introduction of a facial paralysis grading scale for hypoglossal‐facial nerve anastomosis

EMG rehabilitation can improve facial function in patients with facial paralysis, allowing voluntary control of eye and mouth function.

ABNORMAL MOVEMENTS FOLLOWING INJURY TO THE FACIAL NERVE

Both believed that the ticlike movements were peripheral in origin, but both believed that they were central in origin.

Citations

Facial synkinesis: A distressing sequela of facial palsy

Facial synkinesis, a debilitating condition, can be effectively treated with a multidisciplinary approach, involving therapists, clinicians, and surgeons.

Long‐term therapy with botulinum toxin in facial synkinesis: Retrospective data analysis of data from 1998 to 2018

Long-term botulinum toxin A therapy for facial synkinesis does not change the injection regime or dosage, but may require more frequent injections.

Can the Jankovic-assessment be used as an alternative to electromyography? A cross-sectional study on facial dystonia patients treated with Botulinum toxin.

The Jankovic assessment scale is a valid and low-cost alternative to electromyography for assessing facial movement changes in facial dystonia patients treated with Botulinum toxin.

Effect of Botulinum Toxin A (BTX-A) Injection into Denervated Muscles on Synkinesis and Symmetry in Patients with Facial Nerve Paralysis

BTX-A injections may help reduce synkinesis and achieve symmetry in facial nerve palsy patients, but more randomized clinical trials are needed for a firm conclusion.

Outcomes of Buccinator Treatment With Botulinum Toxin in Facial Synkinesis

Buccinator injections with botulinum toxin significantly improve facial synkinesis treatment outcomes compared to treatment without buccinator injections.

Long-term facial improvement after repeated BoNT-A injections and mirror biofeedback exercises for chronic facial synkinesis: a case-series study.

Repeated BoNT-A injections combined with mirror biofeedback exercises can improve facial function in chronic postparetic facial synkinesis patients, even after the injections stop working.

Treating Buccinator With Botulinum Toxin in Patients With Facial Synkinesis: A Previously Overlooked Target

Botulinum toxin injections to the buccinator muscle can effectively improve facial function and cosmetic appearance in patients with facial synkinesis.

Long-term sequelae treatment of peripheral facial paralysis with botulinum toxin type A: Repartition and kinetics of doses used.

This study provides detailed information on effective mean doses for each muscle in peripheral facial paralysis treatment, with a decrease in doses over time, without treatment resistance.

Reanimation of the brow and eye in facial paralysis: Review of the literature and personal algorithmic approach.

This paper presents a systematic algorithm for optimal management of eye problems in facial palsy patients, based on our experience with over 3500 cases.