N. Rowland, M. Fregly
Dec 31, 1993
Citations
1
Influential Citations
42
Citations
Quality indicators
Journal
Brain Research Bulletin
Abstract
Intracerebroventricular administration of the angiotensin AT-2 receptor antagonist, PD 123319, inhibited drinking induced in rats by hypertonic NaCl, carbachol, isoproterenol, hypovolemia, and water deprivation, but had no effect on food intake. In contrast, the AT-1 antagonist, losartan potassium, had no effect on these intakes. A model of thirst is presented that incorporates an AT-2 receptor in a final common pathway for drinking.