Xinjun Tang, Yulin Han, Shengming Ma
Feb 12, 2015
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0
Influential Citations
14
Citations
Journal
Organic letters
Abstract
A cadmium iodide mediated tandem reaction involving amine and two molecules of terminal alkynes for the synthesis of trisubstituted allenes has been developed. By applying this protocol, methyl-substituted allenes may be obtained easily from two molecules of terminal alkynes and pyrrolidine via methyl ketoniminium and propargylic amine formation, 1,5-hydride transfer and β-elimination.