H. Brunner, Darijo Mijolovic, M. Zabel
2001
Citations
0
Influential Citations
5
Citations
Journal
Synthesis
Abstract
Synthesis 2001, No. 11, 28 08 2001. Article Identifier: 1437-210X,E;2001,0,11,1671,1680,ftx,en;Z04601SS.pdf. © Georg Thieme Verlag Stuttgart · New York ISSN 0039-7881 Abstract: New terdentate facially binding ligands based on the 2pyridinyl-ethanol skeleton were prepared as the racemates. Reaction with the enantiomerically pure (–)-(1S,4R)-camphanoyl chloride gave diastereomeric camphanic esters. The pure diastereomers were accessible by separating the diastereomeric esters with medium-pressure silica gel chromatography or fractional crystallization. X-ray structure analysis of the pure camphanic esters established the absolute configurations of the 2-pyridinyl-alcohols. The enantiomerically pure alcohols were obtained after saponification of the diastereomerically pure esters.