H. Gerstein
Jul 10, 2013
Citations
1
Influential Citations
45
Citations
Journal
The New England journal of medicine
Abstract
Recommendations to reduce weight through increased physical activity and dietary restriction have been a mainstay of diabetes care dating back to antiquity.1 In modern times, “lifestyle modification” has been formally recommended as the foundation on which all additional diabetes therapies should rest. These recommendations are supported by physiological studies, clinical experience, observational studies, and randomized, controlled trials showing reduced levels of glucose, blood pressure, and some lipids, as well as improvements in general well-being and other indexes of health. However, most of these studies were of relatively short duration, and no prospective trial has previously assessed the long-term effects of . . .