Isabelle Niespodziany, Philippe Ghisdal, B. Mullier
Apr 16, 2020
Citations
1
Influential Citations
6
Citations
Journal
Epilepsia
Abstract
The antiepileptic drug candidate, padsevonil, is the first in a novel class of drugs designed to interact with both presynaptic and postsynaptic therapeutic targets: synaptic vesicle 2 proteins and γ‐aminobutyric acid type A receptors (GABAARs), respectively. Functional aspects of padsevonil at the postsynaptic target, GABAARs, were characterized in experiments reported here.