L. Zaki, H. Fasold, B. Schuhmann
Dec 1, 1975
Citations
4
Influential Citations
105
Citations
Quality indicators
Journal
Journal of Cellular Physiology
Abstract
Mono‐, di‐, and trisulfonic acids, including 4,4′‐diacetamido stilbene‐2,2′‐disulfonic acid (DAS) and 2‐(4′‐amino phenyl)‐6‐methylbenzene thiazol‐3′,7‐disulfonic acid (APMB) produce a reversible inhibition of sulfate equilibrium exchange in human red cells. A study of the sidedness of the action of a number of these sulfonic acids in red cell ghosts revealed that some, like DAS, inhibit only at the outer membrane surface while others, like APMB, inhibit at either surface. This finding suggests that at least two different types of membrane sites are involved in the control of anion permeability.