Paper
Chemical and biological properties of the world's most expensive spice: Saffron
Published Oct 1, 2010 · J. Melnyk, Sunan Wang, M. Marcone
Food Research International
Q1 SJR score
366
Citations
11
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Literature Review
Highly CitedStudy Snapshot
Saffron's constituents show potential in alleviating or preventing various health problems and promoting cancer prevention and maintenance.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
Worldwide market screening of saffron volatile composition
The extraction method significantly changes the aromatic fingerprint of saffron samples, with the DHD method defining spicier and more floral aromas compared to the USAE method.
2009·77citations·L. Maggi et al.·Journal of the Science of Food and Agriculture
Journal of the Science of Food and Agriculture
Preventive effect of crocin in inflamed animals and in LPS-challenged RAW 264.7 cells.
Crocin exhibits obvious anti-inflammatory effects and may be one of the active ingredients in traditional Chinese medicines like Gardenia jasminoides Ellis and Crocus sativus L., which can modulate inflammatory processes.
2009·95citations·Guang-lin Xu et al.·Journal of agricultural and food chemistry
Journal of agricultural and food chemistry
Role of caspases and Bax protein in saffron-induced apoptosis in MCF-7 cells.
Saffron induces proapoptotic effects in MCF-7 breast cancer-derived cells, suggesting its potential as a potential chemotherapeutic agent in breast cancer.
2009·135citations·S. Mousavi et al.·Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Anxiolytic and hypnotic effect of Crocus sativus aqueous extract and its constituents, crocin and safranal, in mice
Saffron aqueous extract and safranal have anxiolytic and hypnotic effects in mice, with crocin showing no such effects.
2009·282citations·H. Hosseinzadeh et al.·Phytotherapy Research
Phytotherapy Research
Effects of saffron and its active constituents, crocin and safranal, on prevention of indomethacin induced gastric ulcers in diabetic and nondiabetic rats.
Saffron, crocin, and safranal effectively prevent gastric ulcers caused by indomethacin in both non-diabetic and diabetic rats, due to their antioxidant properties.
2009·92citations·S. Kianbakht et al.·Journal of Medicinal Plants
Journal of Medicinal Plants
Citations
Saffron’s protective role against atherosclerosis-induced cataract progression in New Zealand white rabbits with phytochemical analysis of saffron’s extract
Saffron ethanolic extract can reduce cataract progression in atherosclerosis-induced New Zealand white rabbits, potentially due to its bioactive components crocin and crocetin.
2025·0citations·Yasmin Mohd Zainal Abidin Shukri et al.·PLOS ONE
PLOS ONE
A novel and simple method based on the chemometric treatment of UV–visible spectra of acetonitrile extracts to detect plant-derived adulterants in saffron (Crocus sativus L.)
Acetonitrile extraction with UV-visible spectra effectively detects plant-derived adulterants in saffron, enabling the differentiation between authentic and adulterated samples.
2025·0citations·M. Foschi et al.·Journal of Food Composition and Analysis
Journal of Food Composition and Analysis
Characterizing Chinese saffron Origin, Age, and grade using VNlR hyperspectral imaging and Machine learning
This study developed a method using VNIR-HSI, machine learning, and data fusion to identify Chinese saffron origin, age, and grade, with 89.6% prediction accuracy for grade identification.
2025·0citations·Jiahui Wu et al.·Food Research International
Food Research International
Optimizing Saffron Flowering and Yield as Affected by Vernalization and Corm Size of Crocus Sativus L.
Larger saffron corms treated for 16 days of vernalization yield better production than those treated for 12 days.
2024·0citations·Syed Qaiser Ali Shah et al.·Indus Journal of Bioscience Research
Indus Journal of Bioscience Research
Effects of biological fertilizers on physiological traits and bioactive compounds in saffron (Crocus sativus L.).
The 2 year application of K + Fe-Zn solubilizing bacteria as biofertilizer significantly improved both qualitative and quantitative traits of saffron, highlighting its potential importance in sustainable cultivation in mineral-fortified soils.
2024·0citations·Shima Abdoshah et al.·Journal of the science of food and agriculture
Journal of the science of food and agriculture
Assessment of different drying methods with the stability of apocarotenoids and mucilage concentration in Saffron (Crocus sativus L.) stigmas based on mathematical modeling
Drying methods significantly impact the stability of secondary metabolites in saffron, with mild heat at TL50°C and IR50°C enhancing Crocetin and total Crocin, while elevated temperatures negatively impact crocin components.
2024·0citations·M. S. Daneshmandi et al.·Scientia Horticulturae
Scientia Horticulturae
In vitro transdermal release of crocin from electrospun saffron and its comparison with in vitro digestion.
Saffron extract can be successfully delivered through nanofibers, with the Pl-Pc-SE sample showing the highest release during digestion.
2024·1citation·Zahra Najafi et al.·Food research international
Food research international
Influence of Solvent Polarity on Crocin Content and Surface Properties of Saffron (Crocus sativus L.) Extracts
Saffron extracts with different polarities can decrease surface tension and show potential for applications in colloidal systems, with potential for use in formulated foods, nutraceutics, and pharma products.
2024·1citation·R. Rocchi et al.·Molecules
Molecules