Paper
Cinnamaldehyde-induced apoptosis in human PLC/PRF/5 cells through activation of the proapoptotic Bcl-2 family proteins and MAPK pathway.
Published Jul 8, 2005 · Shu-jing Wu, L. Ng, Chun‐ching Lin
Life sciences
Q1 SJR score
76
Citations
0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
In Vitro Study
Highly CitedStudy Snapshot
Cinnamaldehyde triggers apoptosis in human PLC/PRF/5 cells through activation of the pro-apoptotic Bcl-2 family proteins and MAPK signaling pathway.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
9-Hydroxypheophorbide alpha-induced apoptotic death of MCF-7 breast cancer cells is mediated by c-Jun N-terminal kinase activation.
9-HPbD photosensitization induces apoptosis in MCF-7 breast cancer cells, mediated by stress-activated signaling through JNK.
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Involvement of tumor suppressor protein p53 and p38 MAPK in caffeic acid phenethyl ester-induced apoptosis of C6 glioma cells.
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Citations
Cinnamaldehyde potentiates cytotoxic and apoptogenic effects of doxorubicin in prostate cancer cell line
Cinnamaldehyde combined with doxorubicin shows potential as a therapeutic agent for prostate cancer, inhibiting cell proliferation and inducing apoptosis in prostate cancer cells.
2024·0citations·Abbas Abbassi et al.·Research in Pharmaceutical Sciences
Research in Pharmaceutical Sciences
Sublingual Tablets Amalgamated with Nano-particles and natural products to treat Oral Cancer
This sublingual formulation combining Genistein, Cinnamaldehyde, Trans-Resveratrol, and Formononetin effectively treats oral cancer with minimal side effects and lowers the chances of re-occurrence.
2024·2citations·Syed Saif Imam·Research Journal of Pharmacy and Technology
Research Journal of Pharmacy and Technology
Effects of Cinnamon Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Cinnamon supplementation may help modulate blood lipid profiles, with significant reductions in triglycerides and non-significant effects on cholesterol at higher doses.
2024·0citations·Hawal Lateef Fateh et al.·Clinical Nutrition Research
Clinical Nutrition Research
Inhibitory effect of temozolomide on apoptosis induction of cinnamaldehyde in human glioblastoma multiforme T98G cell line
TMZ, when combined with cinnamon extract, has an inhibitory effect on increasing cytotoxicity in human glioblastoma multiforme T98G cells.
2023·0citations·Hedieh Abband et al.·Anatomy & Cell Biology
Anatomy & Cell Biology
Anticancer Potential and Molecular Mechanisms of Cinnamaldehyde and Its Congeners Present in the Cinnamon Plant
Cinnamaldehyde and its congeners show potential as anticancer drugs due to their ability to cause cancer cell apoptosis and inhibit cancer cell invasion and metastasis.
2023·19citations·Sabyasachi Banerjee et al.·Physiologia
Physiologia