M. Petrini, R. R. Shaikh
Sep 1, 2009
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0
Influential Citations
15
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Journal
Synthesis
Abstract
Copper-catalyzed cycloaddition of N-(tert-butoxycarbonyl)-3-(1-tosyl-3-butynyl)-1H-indole with various azides readily provides the corresponding (triazolylethyl)indoles. These derivatives can be regarded as indole-3-propionic acid mimics because of the electronic features of the triazole ring that are closely related to the amido group. The obtained (indolylethyl)triazoles can be further functionalized exploiting an elimination―addition reaction involving the tosyl group.