Hong-yu Zhang, Chao‐Yang Ge, Jiquan Zhao
Sep 13, 2017
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Influential Citations
47
Citations
Journal
Organic letters
Abstract
Disclosed herein is an unprecedented cobalt-catalyzed trifluoromethylation-peroxidation of unactivated alkenes. In this process the hydroperoxide acts as a radical initiator as well as a coupling partner. The cheap and readily available sodium trifluoromethanesulfinate serves as the CF3 source in the reaction. Various alkenes are transformed into vicinal trifluoromethyl-peroxide compounds in moderate to good yields.