Pharmacokinetic comparisons of two different combinations of Shaoyao-Gancao Decoction in rats: competing mechanisms between paeoniflorin and glycyrrhetinic acid.

doi:10.1016/j.jep.2013.06.049

Paper

DOI: 10.1016/j.jep.2013.06.049

Pharmacokinetic comparisons of two different combinations of Shaoyao-Gancao Decoction in rats: competing mechanisms between paeoniflorin and glycyrrhetinic acid.

Published Sep 16, 2013 · Changhua Xu, Ping Wang, Yang-xue Wang

Journal of ethnopharmacology

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Abstract

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Non-RCT

Animal Study

Study Snapshot

Increasing the amount of paeoniflorin in Shaoyao-Gancao Decoction improves the bioavailability and longer efficacy of its active components for spasmolysis and emergency pain relief in rats.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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