Peng Xu, M. N. Trinh, P. Kováč
Feb 1, 2018
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Influential Citations
6
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Journal
Carbohydrate research
Abstract
Properties of di(triethylene glycol monomethyl ether) squarate relevant to conjugation of carbohydrates to proteins have been reinvestigated and compared with those of dimethyl squarate. It is concluded that the commercially available, crystalline dimethyl squarate remains the most convenient and efficient reagent for conjugation of amine-containing carbohydrates to proteins by a two-step or one-pot conjugation protocol.