S. Torii*, Hideo Tanaka, Takuo Anoda
May 5, 1976
Citations
0
Influential Citations
23
Citations
Journal
Chemistry Letters
Abstract
The efficient synthesis of 2-alkyl-3-hydroxy-4H-pyran-4-ones, e. g., pyromeconic acid (6a), maltol (6b), and ethyl maltol (6c), from 2-alkyl-4,5-epoxy-6-methoxytetrahydropyran-3-ones 5 by acid-catalyzed rearrangement is described. The key precursors 5 were obtained by epoxidation of 2-alkyl-6-methoxy-2H-pyran-3(6H)-ones 4, which were synthesized by three steps starting from furfuryl alcohols 1.